Astra Zeneca

Coronavirus vaccine – weekly summary of Yellow Card reporting (Updated 26 November 2021)

Vaccine-Induced Thrombocytopenia with Severe Headache (Germany, 25 November 2021, New England Journal of Medicine)

Complicated Long Term Vaccine Induced Thrombotic Immune Thrombocytopenia—A Case Report (Astra Zeneca) (Germany,  17 November 2021, Vaccines)

Retinal Vascular Events after mRNA and Adenoviral-Vectored COVID-19 Vaccines—A Case Series (Switzerland, 17 November 2021, Vaccines)

Acute-onset polyradiculoneuropathy after SARS-CoV2 vaccine in the West and North Midlands, United Kingdom (U.K, 16 November 2021, Loo et al, Muscle and Nerve)

A case report of vaccine induced thombotic thrombocytopenia due to COVID 19 vaccine as a deceased donor, (12 November 2021, Transplantation Proceedings)

Case study of thrombosis and thrombocytopenia syndrome following administration of the AstraZeneca COVID-19 vaccine (Austria, 12 November 2021, The Royal Australian College of General Practitioners)

Thrombocytopenia with and without Thrombosis Following COVID-19 Vaccination (Canada, 5 November 2021, Ge et al, Thrombosis)

Decline in Pathogenic Antibodies over Time in VITT (Germany, 4 November 2021, New England Journal of Medicine)

Endovascular treatment for vaccine-induced cerebral venous sinus thrombosis and thrombocytopenia following ChAdOx1 nCoV-19 vaccination: a report of three cases (U.K, 2 November 2021, Cleaver et al, Journal of Neurointerventional Surgery)

Massive cerebral venous thrombosis due to vaccine-induced immune thrombotic thrombocytopenia (Italy, 1 November 2021, Bonato et al, Haematolgica)

Vaccine-Induced Thrombotic Thrombocytopenia Following Coronavirus Vaccine: A Narrative Review, (28 October 2021, Annals of Medicine and Surgery)

Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis , (U.K, 28 October 2021, New England Journal of Medicine)

Successful Treatment of Vaccine-Induced Immune Thrombotic Thrombocytopenia in a 26 Year-Old Female Patient (Germany, 6 October 2021, Kemper et al, Acta Haematologica)

Successful treatment of thromboses of major arteries after ChAdOx1 nCov-19 vaccination ,(Germany, 4 October 2021, Neurological Research and Practice)

Severe immune thrombocytopenia after COVID-19 vaccination: Report of four cases and review of the literature , (Italy, 1 October 2021, Blood Cells, Molecules and Diseases)

Vaccine-Induced Immune Thrombotic Thrombocytopenia with Disseminated Intravascular Coagulation and Death following the ChAdOx1 nCoV-19 Vaccine (Saudi Arabia, 30 September 2021, Aladdin et al, Journal of Stroke and Cerebrovascular Diseases)

Characteristics and Outcomes of Patients With Cerebral Venous Sinus Thrombosis in SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia (28 September 2021, van Kammen et al, JAMA Neurology)

Immune thrombocytopenia following immunisation with Vaxzevria ChadOx1-S (AstraZeneca) vaccine, Victoria, Australia (Australia, 26 September 2021, Vaccine)

Imaging findings in a patient with suspected vaccine induced immune thrombotic thrombocytopenia (U.K, 21 September 2021, Kadam et al, British Institute of Radiology)

Predictors of mortality in thrombotic thrombocytopenia after adenoviral COVID-19 vaccination: the FAPIC score (21 September 2021, Hwang et al, European Heart Journal)

The use of IV immunoglobulin in the treatment of vaccine-induced immune thrombotic thrombocytopenia (Germany, 16 September 2021, Blood)

Declining mortality of cerebral venous sinus thrombosis with thrombocytopenia after SARS-CoV-2 vaccination (9 September 2021, Munckhof et al, European Journal of Neurology)

Successful venous thromboprophylaxis in a patient with vaccine-induced immune thrombotic thrombocytopenia (VITT): a case report of the first reported case in Thailand (Thailand, 8 September 2021, Thrombosis Journal)

Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia (France, 1 September 2021, Bersinger et al, Critical Care Medicine)

Post-mortem findings in vaccine-induced thrombotic thombocytopenia (Italy, 2 deceased, August 2021, Haematologica)

Therapeutic Plasma Exchange in Vaccine-Induced Immune Thrombotic Thrombocytopenia (Canada, 26 August 2021, New England Journal of Medicine)

Neurological symptoms and neuroimaging alterations related with COVID-19 vaccine: Cause or coincidence? (Brazil, 23 August 2021, Clinical Imaging)

Adjunct Immune Globulin for Vaccine-Induced Immune Thrombotic Thrombocytopenia (Canada, 19 August 2021, New England Journal of Medicine)

A rare case of vaccine-induced immune thrombosis and thrombocytopenia and approach to management (India, 16 August 2021, Surgical Neurology International)

A case of vaccine-induced immune thrombotic thrombocytopenia with massive artero-venous thrombosis (Italy, 19 July 2021, Turi et al, Blood Transfusion)

Cerebral venous sinus thrombosis associated with thrombocytopenia post-vaccination for COVID-19 (Italy,1 deceased male, 12 April 2021, Castelli et al Critical Care)

Venous Thromboembolism and Mild Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination (Canada, 12 August 2021, Thieme)

Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopenia (Tubingen, 1 August 2021, Haematologica)

Vaccine Induced Immune Thrombotic Thrombocytopenia Causing a Severe Form of Cerebral Venous Thrombosis With High Fatality Rate: A Case Series (Norway, 30 July 2021, Weidman et al, Fronteirs in Neurology)

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know (UK & U.S, 29 July 2021, Blood)

Prothrombotic immune thrombocytopenia after COVID-19 vaccination (Germany, 29 July 2021, Blood)

A case of acute demyelinating polyradiculoneuropathy with bilateral facial palsy after ChAdOx1 nCoV‑19 vaccine (Italy, 17 July 2021, Neurological Sciences)

Vaccine-induced thrombosis and thrombocytopenia with bilateral adrenal haemorrhage (U.K, 8 July 2021, Taylor et al, Clinical Endocrinology)

Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia (Canada, 7 July 2021, Nature)

Case of Guillain-Barré syndrome following COVID-19 vaccine (UK, 29 June 2021, BMJ)

Primary adrenal insufficiency associated with Oxford-AstraZeneca ChAdOx1 nCoV-19vaccine-induced immune thrombotic thrombocytopenia (VITT) , (Spain, 22 June 2021, European Journal of Internal Medicine)

Guillain–Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination (U.K, 30 May 2021, Annals of Neurology)

Ischaemic stroke as a presenting feature of ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia (U.K, 25 May 2021, Mayhani et al, Journal of Neurology, Neurosurgery & Psychiatry)

AZD1222 vaccine-related coagulopathy and thrombocytopenia without thrombosis in a young female (Ireland, 25 May 2021, British Journal of Haematology)

Oxford-AstraZeneca COVID-19 vaccine-induced cerebral venous thrombosis and thrombocytopaenia: A missed opportunity for a rapid return of experience , (France, 24 May 2021, Anaesthesia Critical Care & Pain Medicine)

Immediate high‑dose intravenous immunoglobulins followed by direct thrombin‑inhibitor treatment is crucial for survival in Sars‑Covid‑19‑adenoviral vector vaccine‑induced immune thrombotic thrombocytopenia VITT with cerebral sinus venous and portal vein thrombosis (Germany, 22 May 2021, Journal of Neurology)

COVID-19 vaccine-associated cerebral venous thrombosis in Germany: a descriptive study (Germany, 4 May 2021, Schultz et al)

US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021 (U.S, 30 April 2021, JAMA Network)

Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: population based cohort study (Denmark and Norway, 28 April 2021, BMJ)

Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT) (Austria, 18 April 2021, Thaler et al, Journal of Thrombosis and Haemostasis)

Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination , (U.K 16 April 2021, New England Journal of Medicine)

Myocardial infarction after COVID-19 vaccination-casual or causal? (India, 14 April 2021, Chatterjee et al, Diabetes & Metabolic Syndrome: Clinical Research & Reviews)

Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination, (9 April 2021, New England Journal of Medicine)

Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination , (9 April 2021, New England Journal of Medicine)

Cerebral venous sinus thrombosis and thrombocytopenia after COVID-19 vaccination – A report of two UK cases (UK, 8 April 2021, Brain Behavior and Immunity)

Cerebral venous thrombosis and thrombocytopenia post-COVID-19 vaccination, (Italy, 1 deceased male, 8 April 2021, Thrombosis Research)

AstraZeneca’s COVID-19 vaccine: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets (62 cases of cerebral venous sinus thrombosis and 24 cases of splanchnic vein thrombosis were reported in the EU drug safety database (EudraVigilance) as of 22 March 2021, 18 of which were fatal. As of 4 April 2021, a total of 169 cases of CVST and 53 cases of splanchnic vein thrombosis were reported to EudraVigilance)

Bilateral superior ophthalmic vein thrombosis, ischaemic stroke, and immune thrombocytopenia after ChAdOx1 nCoV-19 vaccination (Germany, 14 April 2021, Lancet)

Thrombocytopenia with acute ischemic stroke and bleeding in a patient newly vaccinated with an adenoviral vector-based COVID-19 vaccine (Denmark, 20 April 2021, Journal of Thrombosis and Hemostasis)

Thrombocytopenia and Intracranial Venous Sinus Thrombosis after “COVID-19 Vaccine AstraZeneca” Exposure (Germany, 9 April 2021, Journal of Clinical Medicine)

A Rare Case of Cerebral Venous Thrombosis and Disseminated Intravascular Coagulation Temporally Associated to the COVID-19 Vaccine Administration (Italy, 8 April, Journal of Personalised Medicine)

Pulmonary embolism and thrombocytopenia following ChAdOx1 vaccination (Austria, 14 April 2021, The Lancet)