Acute-onset polyradiculoneuropathy after SARS-CoV2 vaccine in the West and North Midlands, United Kingdom

U.K, 16 November 2021, Loo et al, Muscle and Nerve Summary We retrospectively reviewed records of all persons presenting with acute-onset polyradiculoneuropathy from January 1, 2021, to June 30, 2021, admitted to two Neuroscience centers, of the West and North Midlands, United Kingdom. We compared subjects with previous SARS-CoV2 vaccine exposure with a local cohort … Continue reading Acute-onset polyradiculoneuropathy after SARS-CoV2 vaccine in the West and North Midlands, United Kingdom

Toxic Epidermal Necrolysis Post COVID-19 Vaccination – First Reported Case

Saudi Arabia, 5 August 2021, Bakir et al, Cureus Summary A 49-year-old woman with no previous medical history presented to the emergency room with a history of fever and skin eruption. She has received COVID-19 Pfizer (BNT162b1) vaccine with a dose of 0.3 mL given intramuscularly one week before the development of her symptoms. The … Continue reading Toxic Epidermal Necrolysis Post COVID-19 Vaccination – First Reported Case

Cerebral venous sinus thrombosis after mRNA-based COVID-19 vaccination

Japan, 16 November 2021, Yagi et al, Neurological Sciences Summary Here, we report a case of CVST with prolonged mild headache after mRNA-based COVID-19 vaccination. A man in his 50 s without remarkable medical history visited our department complaining of 1-week headache, which started 26–30 h after his second dose of tozinameran (Comirnaty® from Pfizer–BioNtech). He was … Continue reading Cerebral venous sinus thrombosis after mRNA-based COVID-19 vaccination

Thrombocytopenia with and without Thrombosis Following COVID-19 Vaccination

Canada, 5 November 2021, Ge et al, Thrombosis Summary Among 9 patients with thrombocytopenia included in this cohort, the median age was 55 years (range 24 to 73), and 5 patients (56%) were female. Seven patients received AZ and 2 had Pfizer vaccines. All events occurred after the first dose of COVID-19 vaccine with a … Continue reading Thrombocytopenia with and without Thrombosis Following COVID-19 Vaccination

Unusual Site of Deep Vein Thrombosis After mRNA Coronavirus Disease-2019 (COVID-19) Vaccination

Japan, Hasegawa et al, Circulation Journal Summary Venous thromboembolism (VTE) complications reportedly occur in unusual sites after ChAdOx2 nCoV-19 (AstraZeneca) vaccination, but few reports on the development of VTE after mRNA COVID-19 vaccination (Pfizer-BioNTech) have been published. A 72-year-old Japanese woman presented with persistent left arm claudication after receiving the mRNA COVID-19 vaccine. Both doses … Continue reading Unusual Site of Deep Vein Thrombosis After mRNA Coronavirus Disease-2019 (COVID-19) Vaccination

Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination

U.S 3 November 2021, Kahn et al, Critical Care Explorations Summary A 20-year-old male college student in good health developed tinnitus and hematuria shortly (2 hours) after vaccination and progressed swiftly to a syndrome of: systemic inflammation; acute kidney injury requiring hemodialysis; acute, bilateral, complete sensorineural hearing loss; radiographic evidence of acute multifocal ischemic strokes; … Continue reading Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination

Occurrence of acute infarct-like myocarditis following COVID-19 vaccination: just an accidental co-incidence or rather vaccination-associated autoimmune myocarditis?

Germany, 31 July 2021, Chamling et al, Clinical Research in Cardiology Summary We would like to present the findings of three different patients that presented to our hospital until mid of June 2021 and showed unusual serious adverse cardiovascular events of infarct-like myocarditis (in the absence of CAD), possibly linked to preceding COVID-19 vaccination. CMR … Continue reading Occurrence of acute infarct-like myocarditis following COVID-19 vaccination: just an accidental co-incidence or rather vaccination-associated autoimmune myocarditis?

Acute Myocarditis Following the Administration of the Second BNT162b2 COVID-19 Vaccine Dose

Saudi Arabia, Miqdad et al, 18 October 2021, Cureus Summary This is an 18-year-old male with no significant past medical history, presented to the emergency department complaining of central crushing chest pain four days following the second dose of the BNT162b2 COVID-19 vaccine. The pain was aggravated by respiration with no radiation or other associated … Continue reading Acute Myocarditis Following the Administration of the Second BNT162b2 COVID-19 Vaccine Dose

Acute myocarditis associated with anti-COVID-19 vaccination

Israel, 28 June 2021, Nevet et al, Clinical and Experimental Vaccine Research Summary Three previously healthy men, 20, 29, and 24 years old, presented to the emergency department due to acute fever and chest pain appearing 2 days after receiving the second dose of BNT162b2. No abnormal heart sounds or evidence of heart failure were … Continue reading Acute myocarditis associated with anti-COVID-19 vaccination

Myopericarditis After the Pfizer Messenger Ribonucleic Acid Coronavirus Disease Vaccine in Adolescents

U.S, 3 July 2021, Schauer et al, The Journal of Pedriatrics Summary We describe 13 patients aged 12-17 years who presented with chest pain within 1 week after their second dose of the Pfizer vaccine and were found to have elevated serum troponin levels and evidence of myopericarditis. All patients underwent CMR within 1 week … Continue reading Myopericarditis After the Pfizer Messenger Ribonucleic Acid Coronavirus Disease Vaccine in Adolescents

COVID-19 vaccine-associated cerebral venous thrombosis in Germany: a descriptive study

Germany, 4 May 2021, Schultz et al, Annals of Neurology Summary We designed web-based questionnaire, which was e-mailed to all Departments of Neurology of University and non-university hospitals in Germany on April 6, 2021. Data collection was closed at midnight on April 14, 2021. We asked to report cases of cerebral sinus-venous thrombosis, cerebral venous … Continue reading COVID-19 vaccine-associated cerebral venous thrombosis in Germany: a descriptive study

Cerebral Venous Sinus Thrombosis After Pfizer-BioNTech COVID-19 (BNT162b2) Vaccination

Singapore, 8 July 2021, Cheng et al, Journal of Clinical Neurology Summary A 61-year-old Chinese male with diabetes mellitus had received his first dose of the BNT162b2 vaccine on March 19, 2021. He reported soreness at the local injection site lasting for a few days, but did not experience fever, headache, or flu-like symptoms. He … Continue reading Cerebral Venous Sinus Thrombosis After Pfizer-BioNTech COVID-19 (BNT162b2) Vaccination

COVID-19 Vaccine-Associated Thrombosis With Thrombocytopenia Syndrome (TTS): A Systematic Review and Post Hoc Analysis

Pakistan, 7 September 2021, Hafeez et al, Clinical and Applied Thrombosis/Hemostasis Summary We utilized the World Health Organization’s criteria for a confirmed and probable case of TTS following COVID-19 vaccination and conducted a systematic review and posthoc analysis using the PRISMA 2020 statement. Of the 175 studies identified, a total of 25 studies with 69 … Continue reading COVID-19 Vaccine-Associated Thrombosis With Thrombocytopenia Syndrome (TTS): A Systematic Review and Post Hoc Analysis

Cerebral venous thrombosis post BNT162b2 mRNA SARS‐CoV‐2 vaccination: A black swan event

Singapore, 26 June 2021, Fan et al, American Journal of Haematology Summary We present three cases of CVT post BNT162b2 mRNA SARS‐CoV‐2 vaccination. Patient 1: A healthy 54‐year‐old Chinese male with well controlled hyperlipidaemia, developed severe headache and vomiting 24 h after his second dose of BNT162b2 mRNA vaccine, and acute left hemiparesis 2 days later. A … Continue reading Cerebral venous thrombosis post BNT162b2 mRNA SARS‐CoV‐2 vaccination: A black swan event

A Small but Significant Increased Incidence of Acute Pericarditis Identified After Vaccination for SARS-CoV-2

U.S, 18 November 2021, Circulation Summary We examined pericarditis cases from December 15, 2020, to April 15, 2021 seen within Intermountain Healthcare, an integrated healthcare system. Pericarditis was defined by at least two of the following criteria: chest pain, EKG changes, pericardial effusion, and pericardial rub; excluded cases secondary to non-infectious causes (e.g., AF ablation). … Continue reading A Small but Significant Increased Incidence of Acute Pericarditis Identified After Vaccination for SARS-CoV-2

Acute myocarditis associated with anti-COVID-19 vaccination

Israel, 31 May 2021, Alon Nevet, Clinical and Experimental Vaccine Research Summary We describe a series of three young male patients, who developed acute myocarditis 2 days after receiving the second dose of the BNT162b2 vaccine. Three previously healthy men, 20, 29, and 24 years old, presented to the emergency department due to acute fever … Continue reading Acute myocarditis associated with anti-COVID-19 vaccination

A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States

Greece, 5 October 2021, Lazaros et al, Vaccine Summary We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273. Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and … Continue reading A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States

Myopericarditis after messenger RNA Coronavirus Disease 2019 Vaccination in Adolescents 12 to 18 Years of Age

U.S, 14 July 2021, Das et al, The Journal of Pedriatrics Summary A cross-sectional study of 25 children, aged 12-18 years, diagnosed with probable myopericarditis after COVID-19 mRNA vaccination as per the Centers for Disease Control and Prevention criteria for myopericarditis at 8 US centers between May 10, 2021, and June 20, 2021. Most (88%) … Continue reading Myopericarditis after messenger RNA Coronavirus Disease 2019 Vaccination in Adolescents 12 to 18 Years of Age

Myocarditis and Pericarditis Following mRNA COVID-19 Vaccination: What Do We Know So Far?

U.S, 18 July 2021, Das et al, Children Summary A cross-sectional study of 29 published cases of acute myopericarditis following COVID-19 mRNA vaccination. The most common presentation was chest pain within 1–5 days after the second dose of mRNA COVID-19 vaccination. All patients had an elevated troponin. Cardiac magnetic resonance imaging revealed late gadolinium enhancement … Continue reading Myocarditis and Pericarditis Following mRNA COVID-19 Vaccination: What Do We Know So Far?

Possible Association Between COVID-19 Vaccine and Myocarditis: Clinical and CMR Findings

U.S, September 2021, Shaw et al, JACC: Cardiovascular Imaging Summary We present cardiac magnetic resonance (CMR) imaging findings in 4 cases of acute myocarditis that were temporally related to the receipt of COVID-19 vaccine. Cardiac Magnetic Resonance Imaging Demonstrating Acute Myocarditis in a 24-Year-Old ManA 24-year-old man with no previous cardiac history developed chest pain … Continue reading Possible Association Between COVID-19 Vaccine and Myocarditis: Clinical and CMR Findings