Diagnosis and Management of Cerebral Venous Sinus Thrombosis With Vaccine-Induced Immune Thrombotic Thrombocytopenia

July 2021, Stroke


Recent reports from the Centers of Disease Control and the US Food and Drug Administration identified 6 cases of CVST associated with thrombocytopenia in US patients who had received the Ad26.COV2.S (Janssen) coronavirus disease 2019 (COVID-19) vaccine. Similar thromboembolic events were reported in Europe following ChAdOx1 nCoV-19 (AstraZeneca) vaccination. Both the Ad26.COV2.S and ChAdOx1 nCoV-19 vaccines contain adenoviral vectors.

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