U.S, September 2021, Dickey et al, JACC: Cardiovascular Imaging
Six previously healthy men (17-37 years of age) with no infectious prodrome developed severe chest pain and elevated troponin I within 2 days-4 days of their second vaccination (Figure 1). Five patients had ST-segment elevation on presentation, with 4 demonstrating no coronary artery obstruction. All patients had negative nasopharyngeal SARS-CoV-2 PCR testing. CMR revealed patchy midmyocardial increased T2 signal with corresponding late gadolinium enhancement consistent with the acute inflammation of myocarditis (Figure 1). Five patients had abnormal left ventricular systolic function.