Unusual Presentation of Acute Perimyocarditis Following SARS-COV-2 mRNA-1237 Moderna Vaccination

Qatar, 23 June 2021, Cureus

Summary

A case of acute perimyocarditis and pericardial effusion in a 29 year old lady, 10 days following the second dose of Moderna COVID-19 vaccination. Once admitted to the emergency department, she started to deteriorate with very low blood pressure readings reaching 40/33 mmHg which was treated with aggressive fluid resuscitation. After 5.5 liters of intravenous fluids, echocardiography and electrocardiogram (ECG) were performed. Findings were consistent with pericardial effusion, signs of impending cardiac tamponade and acute perimyocarditis. Cardiac biomarkers including troponin T and pro-brain natriuretic peptide (BNP) were elevated. Hospital course was complicated with cardiac arrest, acute kidney injury, disseminated intravascular coagulation (DIC) and hemodynamic instability. Eventually, the patient recovered after a three-week hospital stay and was discharged on non-steroidal anti-inflammatory medication (NSAIDs).

https://www.cureus.com/articles/64219-unusual-presentation-of-acute-perimyocarditis-following-sars-cov-2-mrna-1237-moderna-vaccination

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